Buah Merah 500VE is made from Pure Natural buah merah fruit oil exctract enriched with vitamin E in softgel capsule. More Potent than other food supplements because it is certified as Nutritional and Functional Health food by the Ministry of Health Labor and Welfare in Japan.
Buah Merah is grown exclusively in Papua Island in Indonesia and its extracted oil has been utilized by native tribes for so many years.
The research group and co-work group of Nagasaki University, Japan have found higher content of Novel micronutrient, Beta-Cryptoxanthin first in the world.
Buah Merah’s extraordinary medicinal value has attracted great interest from worldwide researchers to study its health benefits. The oil extract of Buah Merah is a good source of carotenoids including ά and β-carotene, as well as β-cryptoxanthin. Many research studies had shown that β-cryptoxanthin is a key carotenoid which fortifies human immune system against chronic and degenerative diseases in modern life. Modern research conducted by Shinshu University of Japan has shown that the oil extract from Buah Merah has extremely high level of β-cryptoxanthin. Epidemiology researchers have conducted in-vitro studies on β-cryptoxanthin to show its significant effect in lowering the risk of lung cancer especially for fanatic smokers.
Beta-Cryptoxanthin has been the focus of the world attention as chemo-preventive natural functional ingredient for cancers of the lungs, prostate, colons, etc.
Dr. Toshiaki Nishigaki had taken an extra mile to study about the medicinal properties and benefits of Buah Merah by authoring a book titled: "Khasiat Buah Merah" (Red Fruit) "博士の愛した赤い果実 プアメラ." This book was published in 2007.
Dr. Toshiaki Nishigaki has first discovered the presence of Beta-Cryptoxanthin, one of carotenoids, in Buah Merah. He is from the Faculty of Medicine, Shinshu University Japan, Chairperson of Tokyo Noni Research Center, Consultant at M&K Laboratories, Inc. Japan and the President of Buah Merah World.
M&K Laboratories Inc. has started to do R/D and disclosed entire characteristics of Buah Merah.
They presented the data on in vitro anti-cancer potential at PATPI (-Perhimpunan Ahli Teknologi Pangan Indonesia - Indonesian Association Of Food Technologists) in 2007 and entire profile of Buah Merah is presented in the books published in Indonesia and Japan.
In addition to in vitro study, they have been studying anti-cancer actions of Buah Merah in cancer cells-bearing mice.
It shows one anti-cancer effect of Buah Merah using human non-small cancer cells, A549 in BALB/C nude mice.
A549 tumor mass was subcutaneously implanted and from Day 14 till Day 60, 0.5mL of Buah Mrah per animal was orally given. The tumor volumes were measured periodically. At Day 61, all the mice were sacrificed and tumor weights were measured.
As shown in Figue, compared to the control, tumor mass of Buah Merah treated group was smaller in volume and there was significant difference in the tumor mass of Day 55. From the average tumor weights at Day 61, the inhibition percentage on tumor proliferation by Buah Merah treatment was 43.6%, though there was no significance.
Acute and subacute toxicity studies of Buah Merah fruit oil extract was conducted in Sprague dawley rats and there is no findings associated were observed. No clinical abnormalities and no behavioral changes were found.
Mutageneticity study were also conducted and results shows that there is no residual pesticides, no trans-fatty acids, no chemicals or heavy metals and no aflatoxins (a poisonous substance that is normally occured in plant) were detected in Buah Merah fruit oil extract.
It was concluded that Buah Merah is a safe food supplement.
